In order to study the effect of loading Angle on the failure mechanism of HTPB propellant bonding interface， microCT was used to scan and reconstruct the bonding interface in-situ during uniaxial tensile process， and the damage evolution process was characterized. Then， the meso-structural parameters and damage variables were introduced into the cohesive force model， and the meso-damage evolution process of the adhesive interface under different loading angles was obtained. The results show that the initial dehumidification of AP particles at the bonding interface mainly starts from the weak interface layer near the interface， and the direction is along the shear component direction of the interface. The fracture pattern of the interface is related to the shear Angle. The smaller the resultant force and the Angle of the interface， the easier the crack propagation to the propellant/liner interface， whereas the crack propagation is more likely to occur between AP particles. Finally， compared with the experimental results， the accuracy of the calculated results is verified， and the damage evolution law of the propellant bonding interface structure under different loading angles is revealed.