The matrix explosives in cast explosives are molten when being ignited under thermal stimulation， thus the hot gas released by reaction expands and reacts in liquid explosives in the physical form of bubble clouds. Considering the scale distribution and activated developing mechanism of burning-bubble clouds， a regulation model for the evolution of burning-bubble clouds after ignition of cast explosives is established. This model well reflected the dependence of reaction evolution and final reaction violence on intrinsic burning rate， shell confinement strength， charging structure size， reserved air-gap volume and pressure relief venting area. Furthermore， the flexibility of this model was verified by comparing the calculated results with the experimental data. Results show that with the increase of shell confinement strength and charge size， the self-sustaining enhanced combustion and reaction violence level increase. Moreover， with the combined design of pressure relief structure venting threshold and pressure relief venting area， the reaction violence of the charge is controlled. Under the charging condition in this paper， when the ratio of pressure relief venting area to shell surface area is up to 8.6‰， the charge reaction violence level is controlled as burning. This work provides a theoretical basis for the thermal safety design and reaction violence evaluation of explosives.