Fluoropolymer-matrix reactive materials are a new type of material with energy release characteristics of impact reaction. It has a wide application prospect in the military field. In order to master the energy release and damage characteristics of fluoropolymer-matrix reactive materials and promote its application in high-efficiency damage warhead， the research status of impact-induced chemical reaction behavior of fluoropolymer-matrix reactive materials and the coupling damage effect of ignition， detonation， invasion and explosion are reviewed. The research progress in energy release characteristics of split Hopkinson pressure bar （SHPB） experiment， quasi-closed ballistic experiment and explosive loading experiment is emphatically introduced. In terms of damage characteristics， the research progress of reactive projectile， fragment and reactive jet is summarized， the application design of fluoropolymer-matrix reactive materials in shaped charge and the research results of reactive jet forming are emphasized. Besides， the related reaction model and numerical simulation are introduced. On this basis， the future research direction is discussed： establishing a systematic response model and simulation method； regulating its performance by formula， process and other parameters； innovating and exploring the observation and characterization technology of energy release reaction and giving engineering application designs.