In complex environment， the micro safety and arming （S&A） device of initiating explosive device needs to have recoverable and anti-overload characteristics. Therefore， this study designed a metal-based electrothermal-driven micro S&A device based on laser processing. The finite element simulation was used to analyze the action characteristics of the nickel-based micro-electrothermal actuator. By adjusting the length and width of the hot arm and the cold arm of the double-arm U-shaped electrothermal actuator and the gap between the arms， the influence of them on the output displacement was explored. Through orthogonal experiments， the optimized ultra-fast laser processing parameters were obtained as follows： frequency 100 kHz， energy 113 μJ， and cutting speed 100 mm·s^-1， respectively. The ultra-fast pulse laser precision manufacturing of nickel-based electrothermal micro S&A device was realized. Finally， the performance verification platform of the micro S&A device was built， the driving displacement and explosion-proof performance of the mechanism under different current excitations were verified. The results show that the driving displacement of the processed micro S&A device can reach 1084 μm under the excitation current of 8 A， and the assembled micro S&A device of initiating explosive device can effectively isolate the explosion in the explosive sequence.