High performance liquid chromatography （HPLC） has several advantages， such as high sensitivity， good reproducibility， high efficiency， and high automation. HPLC is widely used for purity analysis and quality monitoring of chemical materials. 2，4，8，10-Tetranitrobenzopyrido-1，3a，6，6a-tetraazapentalene （BPTAP） as a new heat-resistant explosive has received wide attentions in recent years. However， there is a lack of HPLC method for BPTAP at present. Thus， we investigated and optimized the chromatographic conditions of separating BPTAP， and established a HPLC method for the analysis of BPTAP purity. The method is based on a Plus C18 column （4.6×150 mm， 5.0 µm） by using the mixture of acetonitrile and water （containing 0.1 mg·mL^-1 ammonium acetate） as the mobile phase. Gradient elution mode was used with the detection wavelength at 230 nm. The retention time of BPTAP is 9.13 min with good resolution of all peaks （greater than 1.90）. The method was further verified， and it is found that BPTAP has a good linear relationship between 0.5 µg·mL^-1 and 200 µg·mL^-1 with correlation coefficient （R²） of 0.9997. The detection limit and quantification limit are 0.02 µg·mL^-1 and 0.07 µg·mL^-1， respectively. In addition， the method was used for the purity analysis of BPTAP after the recrystallization， and it is proved that this method has good performance for the analysis of BPTAP.