A novel N-amino compound—4-amino-1,2,3-triazolo[4,5-e]furazano[3,4-b]pyrazine 6-oxide (ATFPO) was designed and synthesized by the reactions of substitution, nitrification-cyclization, neutralization and N-amination using self-synthetic 3,6-dichlorinefurazano[3,4-b]pyrazine as starting material. The structures of intermediates and target compound were characterized by means of IR spectra, ¹H NMR, ¹³C NMR and elemental analysis. The single crystal of key intermediate—tetraethyl ammonium 1,2,3-triazolo[4,5-e]furazano[3,4-b]pyrazine 6-oxide (TTFPO) was obtained, and the crystal structure was analyzed. The crystal of TTFPO belongs to monoclinic system，space group P2(1)/c, cell parameters: a=9.237(2) Å, b=22.162(5) Å, c =7.3506(17) Å, α=90°, β=98.378(4)°, γ=90°, V=1488.6(6) ų, Z=4, μ=0.100 mm^-1, F(000)=656. The study on thermal stability of ATFPO by using differential scanning calorimetry (DSC) method show that its melting point is at 208.77 ℃, the thermal decomposition peak temperatures of ATFPO are 247.13 ℃, 293.68 ℃ and 378.29 ℃, respectively. Based on the calculated (CBS-4M) heat of formation and the experimental density, the detonation parameters of ATFPO were computed using Gaussian 09 program and Kamlet-Jacobs equations. The heat of formation is 705.4 kJ·mol^-1, the detonation velocity is 8743 m·s^-1, the detonation pressure is 34.6 GPa and the detonation heat is 5970 kJ·kg^-1. The mechanical sensitivity was determined according to BAM Fall hammer method, and the impact sensitivity is 35 J. Results show that ATFPO is a novel high energy density material with good thermal stability, insensitivity and preferable detonation properties.