In order to study the detonation and safety performances of dihydroxylammonium 5,5'-bistetrazole-1,1'-diolate (TKX-50) based polymer bonded explosives (PBX), the TKX-50 based PBX was prepared by a slurry kneading method, using fluororesin F2314 as the polymer binder. The detonation performance (detonation velocity, detonation pressure, detonation heat and cylinder expansion tests) and safety performance (impact sensitivity, shock wave sensitivity and thermal sensitivity) were carried out according to the National Military Standard (GJB-772A-1997) and self-built standard test method, and the results were compared with PBX-9501, etc. The results showed that, comparing with PBX-9501, the detonation velocity of TKX-50 based PBX was as high as 9037 m·s^-1 (density of 1.860 g·cm^-3), while the detonation heat (5055 J·g^-1), detonation pressure (26.4 GPa) and the work capacity (1.377 kJ·g^-1) were lower. For the safety performances, the minimum impact energy of raw TKX-50 was only 5 J, while that of recrystallized product was 32 J. The shock wave sensitivity of TKX-50 based PBX was lower (L₅₀=15.1 mm) than that of HMX-based PBX (L₅₀=22.6 mm). Besides, the thermal decomposition temperature (240 ℃) and 5 s explosion temperature (277 ℃) of TKX-50 was lower than HMX (285 ℃, 327 ℃). In this case, TKX-50 based PBX would react more violently under thermal stimulation.