To achieve efficient damage of the ammunition, a directional and focusing multiple explosively formed penetrator (EFP) warhead was designed. The structure and operational principle of the warhead, and the relation between deployment angle and number density of EFP on the target were described. In addition, to obtain the optimal structural parameters of the warhead, the multi-objective optimization model of warhead parameters was established with the velocity and total number of EFP as the objective function, and the Pareto optimal solution was obtained by NSGA-Ⅱ genetic algorithm. Based on the optimized parameters of the warhead, the EFP formation process of the single charge structure under the optimized structure was numerically simulated, and the change of the focusing ability of warhead with the deployment angle of directional segment at different target distance (10, 15 m and 20 m) was analyzed. Results show that the initial velocity of EFP under the optimized structure reaches to 2283.4 m·s^-1. When the EFP is stable, the calculation from formula shows that it can penetrate 35.94 mm thick 45 steel target. At the target distance of 15 m, the optimal deployment angle of the directional segment is 91.15°, and the EFP number density is 169 per square meter.