HMX/F₂₆₀₂ core-shell composite microspheres were prepared via coat of F₂₆₀₂ on HMX particle surface using the suspension spray drying method,and HMX/F₂₆₀₂ composite microspheres were prepared by the blended solution spray drying method. The effects of the suspension spray drying technological conditions including the inlet temperature,feed rate and solution concentration on the particle size of HMX/F₂₆₀₂ core-shell composite microspheres were investigated. The particle morphology,particle size and impact sensitivity of two samples were characterized by scanning electron microscopy (SEM),laser particle size analyzer and impact sensitivity test. Results show that the optimal conditions of suspension spray drying method are the inlet temperature of 85 ℃,the feed rate of 3 mL·min^-1 and the solution concentration of 2%. The HMX/F₂₆₀₂ composite microspheres have internal defects. and its median particle size is 4.75μm. The morphology of HMX/F₂₆₀₂ core-shell composite microspheres is solid sphere with median particle size of 1.23 μm. The drop height of impact sensitivity for HMX/F₂₆₀₂ composite microspheres and HMX/F₂₆₀₂ core-shell composite microspheres is 31.23 cm and 41.37 cm,respectively,revealing that the HMX/F₂₆₀₂ core-shell composite microspheres have better properties.