In order to characterize macroscopic mechanical properties of heterogeneous propellant by microphysical parameters, the compressive property and shock resistance of single-base gun-propellant containing different amount of RDX(0% (binder), 10%, 20%, 30%, 35%) were tested at -40, 20, 50 ℃, and the surface contact angle of binder was measured at 20, 30, 40 ℃ and 50 ℃. Then, the surface energy of binder and the interface energy between binder and RDX were calculated and the microscopic parameter-adhesive energy per mass of RDX and binder(E^d) was defined. The relationships between E^d and mechanical property parameters(yield stress σ, volume deformation impact energy D) were obtained. Results show that σ and D decline in an exponential function with E^d, which is consistent with the macroscopic test: with the increasing of RDX, the E^d decreases, σ and D both increase. It turns out that macroscopic mechanical properties of single-base gun-propellant can be characterized by microphysical parameter.