In order to obtain a potential TNT replacement for melt-cast explosives, the melting process of eutectic based on methyl-nitroguanidine (MeNQ) was studied by differential scanning calorimetry at 50~150 ℃ under different atmosphere (static state and N₂) and heating rates (5, 10, 20, 30 ℃·min^-1). Effects of HNS and HMX on the behaviors of melting of the eutectic were studied. Results show that with the increasing of heating rate, the time of melting and peak temperature of the sample delayed, while the rate of melting increases. HNS and HMX can not accelerate the melting of the eutectic. The melting rate of eutectic based on MeNQ follows the 1/2 order kinetics reaction, and the apparent activation energy of the melting reaction is 11.77 kJ ·mol^-1 at 10 ℃·min^-1.