The chemical stability of di-stabilizers single-based propellant with diphenylamine(DPA) and centralite Ⅱ used as stabilizer heated at 75 ℃, 85 ℃, 90 ℃ and 95 ℃ and the reaction mechanism of the two stabilizers were studied by a multi-temperature artificial accelerated ageing test and gas-chromatography (GC), respectively. Results show that the safe storage life at 30 ℃ obtained by Berthelot′s equation is 42 years. In the initial stage of storage, the chemical stability of di-stabilizers single-based propellant DPA plays a major role in stabilizing the propellant. After DPA is consumed, centralite Ⅱ starts to play. The chemical stability of di-stabilizers single-based propellant is better than that of other normal single-based and double-based propellants. 