The non-isothermal crystallization of 2, 4-Dinitroanisole (DNAN) in RDX was studies by differential scanning calorimetry. Several kinetics models were used to investigate the crystallization behavior of DNAN. The results show that RDX can reduce the super-cooling degree of DNAN and eliminate self-heating of DNAN crystallization. The crystallization kinetics exponent obtained by Avrami equation is 2.34. The mechanism function g(α) was determined. Ozawa exponent of non-isothermal crystallization (m) is 0.77 from Avrami-Ozawa equations. Activation energy (E_a) of DNAN non-isthermal crystallization is 214.99 kJ·mol^-1 with Hu-Zhao-Gao-Zhao equation.