Fractions of β-HMX (β-1,3,5,7-tetranitro-1,3,5,7-tetrazocane) have been used to demonstrate the mutual relationship between friction and impact sensitivities. Inclusion of an additional twelve nitramines into this scenario resulted in a series of partial relationships, which were determined from the molecular structure of these substances. It was also found that there is a relation between increasing heats of fusion of the nitramines studied and their decreasing friction sensitivities. Comparison of friction sensitivity with heats of fusion, ΔH_m,tr of the studied nitramines shows that the increase in ΔH_m,tr values is more or less connected with a decrease in friction sensitivity.