D-optimal method was employed in the experiments of semiconductor bridge (SCB) ignition. The SCB with and without electrostatic discharge (ESD) were used to ignite lead styphnate (LTNR). The ignition voltage, current and time were obtained by oscillograph, and the deck ablation area of SCB was measured by microscope. It was found the ESD could do some damage on SCB, and the higher ESD, the greater deck ablation area is. Compared with the non-ESD SCB, the ignition voltage and energy of ESD SCB were lower, which means that the ESD SCB was more sensitive. The ignition energy and ignition time were measured by t-test, which showed that the ESD of 21 kV was the critical point. With higher than 21 kV, ESD had greater effect on SCB, and the lower, the less.