In order to solve the problems such as the explosive charge safety during penetration, an insensitive explosive charge is designed started with choosing explosive size, size distribution and charging processes to endure high overloading. The impact and friction sensitivities were tested. Results show that after size distribution and deterred, the thinner of the HMX, is the lower of sensitivity will be. The density of charge is improved to 1.8 g·cm^-3 by special technique which controlles explosive charge quality. The experiment research on safety of explosive charge was carried out with test projectiles penetrating reinforced concrete. It indicates that test projectiles are in good condition and the charge is unreactive during penetration.