Three heat-resistant composite explosives (ANPyO(F2311), ANPyO(F2603), ANPyO(F2311:F2603=1:1)) composed of 2,6-diamino-3,5-dinitropyridine-1-oxide (ANPyO), polymer binders and plasticizer were prepared. The performance tests were conducted by measuring the heat resistance, formability, sensitivity, explosion energy and penetration power. Results show that three ANPyO-based heat-resistant composite explosives have better heat resistance and processability,which indicates that three composite explosives can be used in the temperature range of 200-250 ℃,and the mechanical sensitivities of three composite explosives are vicinal and lower than that of ANPyO individual explosive,and the minimum values of impact and friction sensitivity are about 10% and 24%, respectively. The detonation velocity and breaking armour of three composites explosive are higher than that of PYX-based composite explosive, and detonation velocity is increased by about 400 m·s-1, and depth of breaking armour is increased by about 30 mm.