The green synthesis of nitroglycerin from nitration of glycidol with dinitrogen pentoxide (N₂O₅) as the nitrating agent was studied by investigating the effects of different parameters on the nitration of glycidol. Results show that H-ZSM-5 has good catalytic activity，and the preferred catalyst concentration is 15 g·L^-1，and the molar ratio of dinitrogen pentoxide to glycidol is 3：1 and the temperature is 15 ℃. After reaction for 4 h under the above conditions，the selectivity of 100% and yield of 91.1% for nitroglycerin were obtained.