Spherical diazodinitrophenol (DDNP) was prepared from the reaction of picric acid, sodium sulfide,hydrochloric acid and self-developed crystal shape controller F-1. The product with bulk density of 0.70-0.90 g·cm^-3 has a good fluidity, and its average particle size is more than 350 μm. The pressure test of the product can be carried out under condition of more than 40 MPa. In the present manufacturing process, no fine crystals or explosion dusts are produced, and thus it is no need to wash away the fine crystals. The yield of the product prepared from the manufacturing technology is increased by 2%-3% higher than that from the traditional method, and the water need for each unit product is 30-35 kg/kg (DDNP) by circulation use of the mother liquid. Industrial production of spherical DDNP can be realized.