2，6-Diamino-3，5-dinitropyridine-1-oxide (ANPyO) was coated with fluorine rubber F₂₃₁₁ and nitrile-butadiene rubber (NBR) by means of solution-water suspending-distillation method. The structures and properties of ANPyO and coated samples were characterized by Fourier transform infrared spectroscopy (FTIR)，scanning electron microscope (SEM)，differential scanning calorimetry (DSC)，thermograimetry (TG)，and impact and friction sensitivity tests. Results show that the decomposition peak temperatures of coated ANPyO are decreased by 8.3 ℃ and 7.8 ℃，and decomposition heats of coated ANPyO are increased by 282.4 J·g^-1 and 41.5 J·g^-1，and the particles of coated ANPyO become bigger. In FTIR spectra，N—H spectral characteristic absorption bands have 2 cm^-1 and 3.9 cm^-1 red shifts to 3280.6 cm^-1 and 3367.4 cm^-1 respectively，and nitrogen atom in pyridine spectral characteristic absorption band has a 5.8 cm^-1 red shift to 1232.4 cm^-1. The impact sensitivity of coated ANPyO decreases from 16% to 14% and 10%，and the friction sensitivity decreases from 30% to 26% and 28%，respectively.