The interfacial bonding between a series of bonding agents (including polyhydroxy alcohols bonding agents (LBA-22，LBA-201)，hyantoin/triazines composite bonding agents (CBA)，neutral polymeric bonding agents(NPBA) and substituted amides(LTAIC)) and RDX were studied. Meanwhile，all of the bonding agents were used to prepare RDX-CMDB propellants. The surface and interface parameters were measured by the contact angle method and Wilhelmy plat method，and adhesive work was calculated based on the harmonic-mean equation. Results show that the value of contact angle (θ) between CBA and RDX is 35.2°，and the value of adhesive work(Wa) is 135.01 mN/m. In FTIR spectra，(—NO₂) group absorption peak has a 22 cm^-1 red shift to 1510 cm^-1 and the absorption band becomes wide. The mechanical properties of CMDB propellant with coated RDX are significantly improved. The value of σm is increased from 1.02 MPa to 2.01 MPa at high temperature (50 ℃) and the value of εm is increased by 140% at low temperature (-40 ℃). The surface and interface parameters of different bonding agents basically correspond with the mechanical properties improvement of CMDB propellants.