To increase fragment warhead performance,aimable fragment warheads were widely designed and developed to obtain high lethality against air target. A certain focusing fragment warhead driven by two different places of detonation respectively,were numerically simulated by using DYNA3D. To obtain the fragment distribution density,target was modeled numerically at 6 m far away from the fragment warhead. The simulation results show that the fragments can focus on the target,and the fragment ejection angle and azimuth angle agree with each other. The velocity of directional fragment under two asymmetric points initiation is 20.3% faster than that under the center initiation,and the fragment distribution density under two asymmetric points initiation is 9.6% greater than that under the center initiation. Simulation results could be used for the initiation system of focusing fragment warhead in engineering practice.