The interactions of double-base component mixture of nitroglycerin and nitrocellulose (NC/NG) with ammonium dinitramide (ADN) were investigated by pressure differential scanning calorimetry (PDSC),thermogravimetry-derivative thermogravimetry (TG-DTG) and vacuum stability test (VST). The results show that the decomposition exothermic peak temperature of NG in the NC/NG is 207.0 ℃,but drops down to 159.8 ℃ in the (NC/NG)/ADN system. The peak temperature drops down further to 153.6 ℃ at high pressure. The decomposition peak temperature of NC/ADN is a drop in 4.8 ℃ by comparison with NG/ADN. The greater part of ADN is not accelerated to promote decomposition by NG. It is shown that the effect of NC to ADN is strongly than NG to ADN. Besides,the compatibility between NC/NG and ADN was evaluated by VST. The increaser volume of gas products for mixed system is more than 11 mL,and is of “excessive” rating. It is proved that a strong interaction of NC/NG with ADN occurs also at 90 ℃.