The specific property of the O₃/H₂O oxidative treatment of TNT red-water in a rotating packed bed was investigated. The experiments were carried out to examine the effect of various operating variables, such as high gravity factors β,the molar ratios of H₂O₂ to O₃,initial pH value of red-water and ratio of liquid to gas on the removal efficiency of COD in red-water. The results show that the effect of high gravity factors on the removal efficiency of COD in red-water increases with increasing of initial pH value of red-water. However,the effect is not obvious as high gravity factors are higher than 100. And the removal efficiency of COD increases with increasing of ratio of liquid to gas, then decreases with increasing of ratio of liquid to gas. The optimum process conditions are found when the initial pH value is about 11, the molar ratio of H₂O₂ to O₃ is about 1, and the ratio of liquid to gas is about 0.25.