A quantitative method,i.e. confined quasi-static compressing method was used to evaluate the statistical coherence strength of energetic crystalline granules. Termed Initial Secant Modulus (ISM) based on compressive stiffness curve was defined to characterize the mechanical property or coherence strength of energetic granular aggregation. Mock crystalline materials, i.e. salt, sugar and monosodium glutamate (MSG) for HMX, RDX and NTO respectively were selected to verify this method. Three types of crystalline RDX granules, i.e. sample a (recrystallized from mixed solvent), sample b (sphered by solvent soaking method) and sample c (industry grade coarse granules) were compressed in a thick-wall steel cylinder, and ISMs of the three types of RDX aggregation were measured to be 89.5 MPa， 85.0 MPa and 48.0 MPa, respectively. The results show that recrystallization processes improve coherence strength and quality of RDX crystalline granules compared to industry grade coarse RDX, while two recrystallization processes cause little difference in coherence strength of processed granules.