2，4-Dinitroanisole （DNAN） has emerged as a novel insensitive melt-cast carrier explosive， serving as a practical and effective replacement for TNT in various applications. However， the conventional batch reactor synthesis method is plagued by several limitations， including prolonged reaction duration， excessive in-process inventory， and significant generation of byproducts， which collectively restrict its safe and efficient large-scale production. Consequently， developing advanced preparation processes has become imperative. This study investigates the synthesis of DNAN employing a reaction system comprising 2，4-dinitrochlorobenzene （2，4-DNCB）， methanol， and sodium hydroxide， with a particular focus on continuous flow technology and reaction kinetics. Through mechanistic simulations， a kinetic reaction model was successfully established. The experimental kinetic results indicate that the etherification of 2，4-DNCB follows second-order reaction kinetics， where the reaction rate is proportional to the product of the concentrations of 2，4-DNCB and NaOH. Key kinetic parameters were determined as follows： Activation energy （E_a）： 73.950 kJ·mol^-1. Pre-exponential factor （A₀）： 7.991×10¹⁰ L·mol^-1·s^-1.The effects of critical process variables—namely， reaction temperature， residence time， and molar ratio of reactants—on the product purity and yield were systematically investigated. The optimal reaction conditions were identified as： Reaction temperature： 90 ℃. Residence time： 1 min. Molar ratio （2，4-DNCB∶NaOH）： 1.6∶1. Under these optimized conditions， DNAN was obtained with a yield of 93.7% and a purity exceeding 99.99%. This research provides a robust theoretical foundation and practical methodology for the continuous and efficient production of DNAN.