The mitigation technology of controlling the reaction level of munitions under accidental stimulation is one of the key technologies of insensitive munitions, which plays an important role in improving the safety of munitions. In order to provide reference for improving the comprehensive performance of munitions, the principles and methods for structural mitigation and protection design aiming at reducing the intensity reaction level of munitions under thermal, mechanical and combined stimuli were summarized, based on the analysis of the research progress of mitigation technology abroad. The core ideas of mitigation designs were reducing stimuli energy and controlling the process of reaction evolution of charges. On this basis, three directions were recommended including research in the ignition and mechanism of reaction evolution of charges, the composite shell technology, and the combined design technology for charge-structure-mitigation.