To study the quasi-static compression response behavior of polymer bonded explosive (PBX) under different end face friction conditions, a typical casting PBX explosive was selected as the research object, and the quasi-static compression tests were carried out under three kinds of end face friction conditions； molybdenum disulfide lubrication, dry friction, and grease lubrication. The load-displacement curves were measured by using electronic universal material testing machine. Based on the isotropic elastic theory, the friction mechanism of the end face was preliminarily discussed by the energy conservation method. Results show that the static failure strain is closely related to the friction coefficient. Under the same friction conditions, the material with viscoelastic properties, high Poisson′s ratio, great axial strain and small length-diameter ratio has an obvious end face friction effect in the static compression test.