To reduce the charge amount of welding explosive, TA2 titanium and Q345 steel plates were used as flyer and base plates of dovetail groove, respectively. The upper side length, the lower side length and the height of dovetail grooves were 2 mm, 3 mm and 1mm, respectively. All the intervals between dovetail grooves were 3 mm. The Ti-steel clad plate with dimension of 7.0 mm×300 mm×750 mm was obtained via Q345 steel and TA2 titanium plates with dovetail groove were loosely fitted and bonded by explosive pressure welding and hot rolling technology. Bonding quality at the interfaces of Ti-steel clad plate was analyzed by mechanical property test and microscopic morphology observation. Results show that the metallurgical bonding at the interfaces of TA2 titanium and Q345 steel plates is achieved by explosive pressure welding and hot rolling. Bonding quality at the interfaces of the clad plate is good, and the interfaces exhibit a linear shape, and intermetallic compounds do not occur. The clad plate has excellent bending performance. Compared with explosive welding, the charge amount of Ti-steel clad plate produced by explosive pressure welding and hot rolling may save by 62.7%.