In order to extend the application of 2, 6-diamino-3, 5-dinitropyrazine-1-oxide (ANPZO), three different ANPZO crystallines with cubic, needle and ultrafine shape were obtained by recrystallization and pneumatic spray refining. Some sensitivities and performance of ANPZO explosive were characterized, such as shock wave sensitivity, mechanical sensitivity, thermal behavior and detonation velocity. Results show that the shock wave sensitivities for different ANPZO crystal shapes are nearly the same with approximate 3.65mm in D₅₀. The mechanical sensitivity of cubic ANPZO crystal is lower than that of other crystals. ANPZO is thermally stable with maximum heat release peak value of 350 ℃, the 5 s delay explosion temperature as 302 ℃ and the decomposition temperature as 305 ℃ in slow cook-off test. Detonation velocity measured is up to 8070 m·s^-1 with the density of 1.855 g·cm^-3.