To find suitable components for energetic eutectic mixtures, 3-amino-2,4,6-trinitroanisole with an overall yield of 76% was synthesized via the sequence methylation-VNS amination of commercial picric acid. And its properties were preliminarily studied by IR, 1H NMR and elemental analysis. The mechanism of methylation and VNS amination were discussed. DSC-TG curves show that the endothermic peak temperature is 133.77 ℃ and the exothermic peak temperature is 254.10 ℃. The massloss is about 1.71% at 199.6 ℃. H₅₀ is 82.5 cm and the friction sensitivity is 0%. V₅₀ is 11.42 kV and E₅₀ is 1.99 J. The theoretical detonation velocity is 7.459 km·s-1 (ρ=1.709 g·cm ^{-3), and the theoretical detonation pressure is 22.9 GPa (ρ=1.709 g·cm -3). Results show that 3-amino-2,4,6-trinitroanisole is stable to heat. The theoretical detonation velocity and pressure of 3-amino-2,4,6-trinitroanisole are larger than that of TNT.}