The oxidation temperature and oxidation induction time of n-dodecane,a main component in aviation fuel,were determined by means of pressure differential scanning calorimetry (PDSC). The oxidation activation energy and pre-exponential factors of n-dodecane were obtained by two ways from Flynn-Wall-Ozawa equation to be 154.37 and 154.56 kJ·mol^-1,16.60 and 16.64 min^-1, respectively. The oxidation activation energy of n-dodecane was calculated from Arrhenius modifying equation to be 139.59 kJ·mol^-1. The thermal stability of n-dodecane were evaluated from the view of chemical dynamics.