To select and optimize the formulation components of high-energy Fuel air explosive， petroleum ether， propylene oxide， and ethyl ether （liquid fuel）， isopropyl nitrate and nitromethane （liquid sensitizer）， and metallic aluminum powder （solid component） were used as the research objects. The explosion pressure and explosion temperature of FAE with different composition ratios was investigated by EXPLO5 calculations. The cloudburst experiments of liquid and liquid-solid FAE formulations were also conducted under unconstrained conditions， and the parameters such as explosion field and temperature field were analyzed for the damage effect. The results show that the mixed liquid FAE， composed of petroleum ether （mass accounted for 55%-70%）， propylene oxide， and isopropyl nitrate， shows a better detonation performance.. The liquid-solid mixture of FAE with a liquid-solid ratio of 1∶1 has a better detonation performance and shows the best cloud dispersion state in the unconstrained cloud dispersion experiment. Two systems of FAE formulations in the 1 kg of secondary detonation charge under the cloud burst can be a stable response to achieve the detonation state. They all have superior results in terms of destructive capacity. Also， the effects of heat damage and overpressure damage were quantified and evaluated for each system.